Biology 4445/ 5445 ‑ Pathogenic Microbiology Fall
2007
Instructor: Dr.
R.J.C. McLean
Supple
Email: McLean@txstate.edu
Office hours M - Th
Prerequisite: Microbiology
2400 or equivalent (as determined by instructor)
Text: Salyers and
Whitt, Bacterial Pathogenesis - A Molecular Approach, 2nd Edition,
ASM Press,
Lecture and Laboratory notes: Bio 4445/5445 Coursepack available in
bookstore.
Recommended reference:
A Photographic Atlas for the Microbiology Laboratory, M.J. Leboffe and
B.E. Pierce, latest Edition, Morton Pub.
Course Description:
This course will cover pathogenic bacteria and their relationshiop to
disease, emphasizing identification of selected groups of pathogens,
epidemiology and the biological basis for resistance [from TX State catalog].
Grading:
Mid term 1 (Sept 27) 15%
Mid term 2 (Nov 1) 15%
Laboratory 25%
Class Presentation 15%
Final (take
home, due 12/11 at
Students must
achieve a passing grade in both the lecture (mid terms and final) and
laboratory portion of the course in order to pass.
Class Presentation:
‑ will consist of students giving an oral presentation (5 ‑
10 minutes) of a journal primary research paper which is related to some aspect
of pathogenic microbiology that has been published in the current calendar year
(2007). Students should be prepared to
discuss how the experiments were conducted, what the results mean, etc. Grading will be based equally on the quality
of presentation, and participation in class discussions. [Students in 5445 will also be expected to
turn in a short 2 page typewritten evaluation of their research paper.]
Topics covered in class:
Pathogen structure
& metabolism
Antimicrobial
Agents
Immunology and
Infection
Normal flora
Host‑parasite
Disease
transmission
Role and Function
of Clinical Microbiology Laboratory
Mid term 1
Staphylococcus; Streptococcus;
Neisseria; Haemophilus; Bordetella; Listeria and Corynebacteria; Mycobacterium;
Enterobacteriaceae; Vibrionaceae; Pseudomonas; Oral Microbiology and Nosocomial
Infections
Mid term 2
Final
Exam
will be a take home exam in which you are required to write an NIH-style grant
proposal based on an R03 (small grant format) to study one aspect of pathogenic
microbiology. This is due at
Attendance
Policy: Attendance at all laboratories
is mandatory. Two or more absences from
laboratory will result in a lower letter grade for the course.
Academic
Honesty: Students are advised to consult
the
Withdrawing
from the course: Students must
see the instructor prior to withdrawing otherwise a grade of F will be
automatically assigned. Students will
otherwise be allowed to drop Bio 4445/5445 with a grade of W until October
15. After that time, students who drop
the course will receive a W only if
they are passing both the lecture and laboratory portion of the course.